Expresión de búsqueda: 1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE 
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Descriptor Inglés:   1-Alkyl-2-acetylglycerophosphocholine Esterase 
Descriptor Español:   1-Alquil-2-acetilglicerofosfocolina Esterasa 
Descriptor Portugués:   1-Alquil-2-acetilglicerofosfocolina Esterase 
Sinónimos Inglés:   PAF Acetylhydrolase
Platelet-Activating Factor Hydrolase  
Categoría:   D08.811.277.352.100.680.750.937.249
Definición Inglés:   A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. 
Nota Histórica Inglés:   2004(1983) 
Calificadores Permitidos Inglés:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Número del Registro:   38141 
Identificador Único:   D043203 

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